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Microenvironment-responsive phototherapeutic platforms that sense biochemical cues including redox status allow activation only within pathological niches, improving safety and enabling synergistic combinations with GSH-consuming or GSH-responsive agents to bias tumor redox balance toward therapeutic ROS generation [21]

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Thus, preliminary data from a phase 1b trial showed that use of cagrilintide and semaglutide in obese subjects resulted in greater weight loss than semaglutide alone, 17Percentage versus 10Percentage after 20 weeks [5]

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