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638 Blocking 1R prevents DN in rats and is a potentially effective treatment for peripheral neuropathies in diabetes patients

The progression to dual agonists represented by tirzepatide (GLP-1 + GIP) demonstrated that targeting additional metabolic receptors could significantly amplify research outcomes

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Similarly, acid reflux medication s taken in infancy also alter the microbiome and double the risk of asthma in childhood.[ref] Related article: How Genetics Impacts Gut Microbiome IL-13 and NSAID-exacerbated respiratory disease