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In addition, consistent with the findings reported elsewhere, we found DMF induces the activation of NRF2, and NRF2 targets such as those involved in cystine uptake (SLC7A11) and GSH biosynthesis (GCLM and GCLC, the mediator and catalytic subunits of GCL) (Fig

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Anti-LOX activity was induced through intragastric gavage using a specific LOX inhibitor, beta-aminopropionitrile fumarate, at a dosage of 100 milligrams per kg per day