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However, this extrapolation from one organ to another is questionable as the exposure levels, the phase I metabolic capacity to generate NAPQI, the phase II metabolic capacity to eliminate APAP, and potential adaptive mechanisms in response to an APAP-induced cellular stress are not well described in the CNS system

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Philos Trans R Soc Lond Ser B Biol Sci 369:20130226 Gabara B, Kuniak E, Skodowska M, Surwka E, Miszalski Z (2012) Ultrastructural and metabolic modifications at the plantpathogen interface in Mesembryanthemum crystallinum leaves infected by Botrytis cinerea

importante notare che i farmaci a base di carnitina sono disponibili anche sotto forma di fiale iniettabili, ma questi sono riservati all'uso clinico e somministrati solo sotto supervisione medica