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E-Sol5 and supercooled storage boost the ratios of reduced to oxidized glutathione, while only supercooled storage prevents cystine efflux Considering the results from the PPP, we investigated the redox homeostasis with an emphasis on glutathione metabolism, a critical pathway for protecting cells from oxidative damage and ensuring their survival (Fig

Front Physiol 15:1346173 Bratosin D, Estaquier J, Petit F et al (2001) Programmed cell death in mature erythrocytes: a model for investigating death effector pathways operating in the absence of mitochondria