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The types of side effects are almost identical, mainly digestive issues like nausea, diarrhea, and vomiting

10.3389/fneur.2015.00178 Front

It is more commonly found in people over age 60, with a prevalence of about 2-5 in 10,000 people.[ref][ref] Symptoms of polycythemia vera can include:[ref] Itching, especially after heat exposure, due to histamine release Gouty arthritis or toe joint pain Burning in the hands or feet Fatigue, weakness, headaches Bloating or fullness due to an enlarged spleen However, many people with polycythemia vera (up to 50% according to one study) have no symptom s when they are diagnosed

Affected individuals display a spectrum of disease severity corresponding to the degree of reduction in G6PD activity, which is determined by the specific G6PD variant alleles present 7,8,9