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In healthy systems, homocysteine is quickly recycled back into methionine (via methylation) or converted into cysteine and glutathione (via the transsulfuration pathway)

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Histological analysis reveals that aged kidneys accumulate senescent cells primarily in tubular regions, identified by loss of Lamin B1 (LMNB1), elevated senescence-associated -galactosidase activity, and expression of inflammatory IL-6

We report that NAC effectively prevents the harmful effects of adolescent THC exposure, highlighting its potential as a therapeutic intervention for treating long-term neuropsychiatric consequences of chronic developmental cannabis exposure