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Beyond 24 Weeks: Maintenance Phase Weight loss typically plateaus between 612 months as energy expenditure adjusts to the lower body weight

Discussion This meta-analysis demonstrates that, while GLP-1 receptor agonists and other anti-obesity agents are effective in inducing substantial initial weight reduction, patients commonly experience clinically relevant weight regain from the lowest weight achieved, both during ongoing treatment and following discontinuation

The MHRA operates the Yellow Card scheme , which allows patients, carers, and healthcare professionals to report suspected adverse drug reactions (ADRs) and interactions