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In addition, the high expression of NRF2 enhances the expression of downstream SOD1, an important antioxidant enzyme that plays a crucial role in protecting cells from oxidative damage [36]

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A standard curve was created using serial dilutions of plasmid DNA containing the target mtDNA sequence, and amplification efficiency was validated with a correlation coefficient above 0.98

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Mechanism: A mitochondrial-derived peptide that acts as a metabolic regulator

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