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4.5 Regulation of skin and gut microbial homeostasis In AD, the disruption of skin and gut microbial homeostasis is increasingly recognized as a critical factor contributing to the initiation and persistence of chronic inflammation and epithelial barrier dysfunction (Pessa et al., 2023

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Regulatory bodies including the MHRA and European Medicines Agency (EMA) continue to monitor safety data, and current product information for GLP-1 agonists includes cholelithiasis and cholecystitis as recognised adverse reactions

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