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Many, including the supplement Konzier took, feature the plant-derived compound berberine, also called natures Ozempic. Some studies have found berberine can increase GLP-1 production in rats, and potentially drive moderate weight loss in humans, but researchers have called for more conclusive evidence

It's important to acknowledge that these are common, with studies indicating that a significant percentage of users (reports range from 40% up to 85%) experience issues like nausea, vomiting, diarrhea, constipation, bloating, or heartburn, particularly when first starting the medication or increasing the dose

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