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Satiety and Brain Signaling Beyond the stomach, semaglutide interacts with the areas of the brain that regulate appetite and food noisethose constant, intrusive thoughts about what to eat next

After the initial reduction in appetite, the food intake of the experimental groups increased to the same amount as the rats in the control group, however, both the high dose and low dose groups were seen to have maintained a lower level of body weight despite the increase in calories