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Cluntun AA, Lukey MJ, Cerione RA, Locasale JW

Even if Zepbound growth begins to moderate over time, the company will have a major next-generation candidate ready to sustain sales momentum

Although Sorafenib is a kinase inhibitor with multiple targets including RTKs and RAF, its treatment did not affect the total tyrosyl phosphorylation and ERK phosphorylation in TamR cells (Figure S5), indicating that inhibition of TamR ER+ breast cancer cell growth by Sorafenib under the concentration used is not through inhibition of RTKs and RAF