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Yet, more research is needed to evaluate and confirm the safety and effectiveness of such dosing regimes

Notably, for some forms of plasticity in interneurons, the relation between the magnitude of [Ca 2+ ] i rise and induction of LTP or LTD could be different from that in pyramidal neurons, e.g., lacking the LTD window altogether (Le Roux et al., 2013) or even the inverse (whereby lower influx induces LTP and LTD occurring after higher rises)