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Both the Li et al

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The dissociation of IRP-IRE interaction will promote the translation of ferritin and FPN mRNA and destabilize TfR and DMT1 mRNA, resulting in the decline of iron absorption and increase of iron storage and export [67, 68]

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doi: 10.1152/physrev.00023.2017 297 YangL.LiuS.ZhangZ.WanX.HuangB.ChenY.et al

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Research shows that at least 10% of people over 60 have B12 deficiency, and many younger adults are also affected due to dietary choices or absorption problems

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