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Common Antidepressants: Safety Profile With Semaglutide SSRIs such as sertraline, fluoxetine, and paroxetine are among the most widely prescribed antidepressants, and clinical evidence shows they combine safely with GLP-1 medications including semaglutide

Medicaid coverage of GLP-1s varies, with several states planning to restrict coverage amid the drugs high costs and recent cuts in federal health care spending

Preclinical studies show promise for GLP1-based therapies in slowing cognitive decline and enhancing brain health, though more research is needed before clinical use in neurodegenerative diseases