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Mortality status and cause of death were determined by NHANES-linked National Death Index public access files through December 31, 2019

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In the last few years, various GSH modulation-enhanced combinational therapy strategies have been extensively exploited, accompanied by the development of versatile metal-based nanosystems with different structures, functionalities, and treatment performances ( In view of the rapid development of GSH-responsive and -exhausting metal nanomedicines in potentiating cancer therapy, we summarize and outline the recent advancements, mechanisms, prospects, and challenges in this field from different strategies (Scheme 1)

In addition to the elevated blood pressure readings obtained from the sphygmomanometer, patients with hypertension often experience other issues such as endothelial dysfunction, increased peripheral vascular resistance, and arterial stiffness