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Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase

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Statistical assessment shows significant difference in dose, duration groups and in interaction between dose and duration groups of DNA migration in brain cells where F-value is greater than F-critical value in brain tissue (Table 8)

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