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Another potential therapeutic, Minocycline is a microglial inhibitor which reduces BBB dysfunction by preventing production of glutamate, matrix metalloproteinases, and the proinflammatory cytokine, IL-1, and increasing the levels of cells responsible for the remyelination of neurons which would be relevant in treating AD [138, 140,141,142]

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It has a well-documented role in tissue repair, collagen synthesis, and angiogenesis, and topical formulations are widely marketed for androgenetic alopecia

doi: 10.1007/S13530-025-00264-W 88