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nNOS: a neuronal cytosolic variant commonly localized to post-synaptic densities, and generally accepted to be the most involved enzyme in physiological co-transmission iNOS: a cytosolic variant expressed in a range of cells including transmission-relevant astrocytes and microglia, from which it likely plays an indirect co-transmission role eNOS: a primarily endothelial membrane-localized variant that is likely the least relevant for co-transmission NOS synthesizes NO by deiminating L-arginine into L-citrulline, short circuiting the urea cyclewhen it is present

Semaglutide (Wegovy) is given once weekly, while liraglutide (Saxenda) requires daily administration

Omega fats can be found in plant sources such as flax, but its not easily used by our bodies because it must be converted into DHA or EPA, which is an inefficient process

This difference may affect response patterns