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Across GLP-1 trials, about 60% of lost weight returns within the first year and roughly 75% returns over the longer curve, with the fastest regain in the early months. In semaglutides extension, about two-thirds returned within one year. The pattern reflects removal of appetite suppression after major weight loss

The National Library of Medicine notes that tirzepatide works as an incretin mimetic that helps the pancreas release insulin and slows stomach emptying to curb appetite

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And earlier this month, federal health authorities issued a warning about counterfeit versions of Ozempic that have been circulating throughout the U.S