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Kraus et al., Nature (2014), on NNMT and diet-induced obesity

Because most of the thiamin is lost during the production of white flour and polished (milled) rice, white rice and foods made from white flour (e.g., bread and pasta) are fortified with thiamin in many Western countries

These findings indicate that TBK1 is a unique target of anti-inflammatory flavonoids resulting in the inhibition of the TRIF-dependent signaling pathway ( LPS-induced inflammatory responses are controlled at the transcriptional level through the MAPK and NF-B pathways (184)

Why We Need to Change the Way We Talk About GLP-1 Medications After talking with Summer, it really solidified the fact that we need to approach the topic of GLP-1s and obesity with more nuance and less judgement in our society