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Patients and their families should receive comprehensive information about the condition, its implications, and how to recognize allergic reactions

The risk rises when it is used with insulin or insulin secretagogues, such as sulfonylureas

J Clin Endocrinol Metab 91(5):19161923 Lorenz M, Pfeiffer C, Steinstrasser A, Becker RH, Rutten H, Ruus P et al (2013) Effects of lixisenatide once daily on gastric emptying in type 2 diabetes--relationship to postprandial glycemia

Mice heterozygous for a disrupted UA oxidase transgene (UO X +/) exhibited diminished brain damage and enhanced functional recovery following ischemic stroke, prompted researchers to explore the potential role of UA treatment in animal stroke models [145]