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Whereas M2 macrophages can exert cancer-promoting effects in several ways, such as directly promoting cancer cell metastasis (190), promoting angiogenesis (191), and inhibiting tumor-killer cell activity (192), this suggests that bilirubin may promote cancer through this mechanism

NAION represents an equally devastating complication, causing sudden and irreversible vision loss when blood flow to the optic nerve stops, requiring patients to seek medical attention immediately

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On the other hand, bacteriostatic water is perfect for multi-dose vials because it contains 0.9% benzyl alcohol, which prevents bacterial growth