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11 Preliminary real-world data further suggest that biweekly interval dosing of GLP-1 therapy can maintain prior weight loss for an average of 32 weeks, with an average of 2% additional weight loss and 84% of patients remaining on biweekly interval dosing

To put that into perspective, someone who started the trial at 300 pounds could theoretically lose about 60 pounds on tirzepatide versus roughly 41 pounds on semaglutide over about a year and four months

GLP-1 drugs like semaglutide (Wegovy) and tirzepatide (Mounjaro) have been called game-changers

It works by mimicking a hormone in the body glucagon-like peptide-1 (GLP-1) that helps control appetite and blood sugar levels