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One function of NADPH is to reduce GSSG to GSH, a reaction catalyzed by glutathione reductase (reaction 10)
doi:10.1016/0165-0173(93)90013-p
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Results Neuronal GCLC knockout leads to brain atrophy accompanied by neuronal cell death To examine how the declines in GCLC and glutathione might affect brain homeostasis, we prepared GCLC floxed X CaMKII-Cre (GCLC-KO) mice whose GCLC expression is deleted in calcium/calmodulin-dependent protein kinase II (CaMKII)-positive neurons
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