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Endothelial-to-mesenchymal transition is induced by high glucose, TGF- signaling, and inflammatory cytokines, and is implicated in fibrosis and plaque instability (33, 34)

Therapeutic efficacy of an angiotensin II receptor antagonist in patients with nonalcoholic steatohepatitis

Patients can be directed to administer a defined number of sprays per nostril at specified times typically once or twice daily, often timed to evening or pre-sleep for alignment with endogenous GH pulse patterns