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By way of non-limiting example, the use of the following commonly used solvents should be limited, reduced or eliminated when formulating agents for administration to the ear: alcohols, propylene glycol, and cyclohexane

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Similar cardiovascular outcomes in patients with diabetes and established or high risk for cor- onary vascular disease treated with dulaglutide with and without baseline metformin

The label recommends reducing the dose from 5 mg twice daily to 2.5 mg twice daily when co-administered with these agents, except in patients already on 2.5 mg for age, weight, or creatinine criteria