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In summary, rational design has led to the development of two long-acting GLP-1 analogs, liraglutide and semaglutide, that have made a vast contribution to the management of T2D in terms of improvements in glycemic control, body weight, blood pressure, lipids, beta-cell function, and CV outcomes

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There are also other benefits to consuming a mix of prebiotic fibers beyond stimulating satiety hormones, from improved gut health to general improvements in metabolic health, he observes, with resistant starchlong the unsung hero of nutrition sciencefinally getting its moment in the sunshine

For clinicians, it underscores the need for integrated care models that link metabolic and liver health