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Scientific identity Synthetic alpha-MSH analogue Alternative names NDP-alpha-MSH and afamelanotide Peptide length 13 amino-acid residues Main receptor Melanocortin-1 receptor Primary effect Increased eumelanin production Approved UK use Prevention of phototoxicity in adult EPP Cosmetic tanning approval Not authorised Main evidence warning Online products are not equivalent to Scenesse What Is Melanotan I

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Preclinical investigations have shown that niosomal formulations of tazarotene and calcipotriol have improved skin penetration and anti-inflammatory properties (72)