death from semaglutide Nurse's linked to weight-loss drug Mounjaro approved on NHS Obesity Drug Wegovy Prevents Covid

Patients should be monitored for these side effects and managed appropriately

A 2025 systematic review published in Cureus analyzed five studies encompassing 2,905 adult patients using GLP-1 receptor agonists

2024 Meta-Analysis Indicates That GLP-1RAs Reduce Adverse CV Events A 2024 Meta-analysis of 13 multiple cardiovascular outcome trials has documented that GLP1-RA therapy significantly reduces the risk of major adverse cardiovascular events (MACEs), all-cause mortality, CV mortality, stroke, risk for coronary revascularization, and composite adverse kidney outcomes in both sexes, regardless of a patient's history of cardiovascular disease, BMI or eGFR (Rivera et al, 2024)

These findings align with previous studies showing that weight loss, whether induced by diet or exercise, can improve mitochondrial efficiency in skeletal muscle (10, 23)