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It's also sometimes sold as a supplement, which is popular with bodybuilders and athletes, who believe it may help them to control their body temperature and reduce muscular fatigue during exercise

Rev Obstet Gynecol

NPT4 is located at the apical side of renal tubules, and functions as an apical voltage-driven urate efflux transporter, also known as NPT4-Na + /phosphate co-transporter (Jutabha et al., 2010)