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ISBN 1-59197-281-7

Table 2 Signal detection for GLP-1 RAs-associated gastrointestinal adverse events

Thuesen BH, Husemoen LLN, Hersoug LG, Pisinger C, Linneberg A

Importantly, Ca 2+ - and ROS-dependent LMP has been reported to contribute to necroptosis via release of cathepsins, cathepsins-mediated mitochondrial dysfunction, and lysosome-dependent regulation of RIPK1 and RIPK3 post-translational modifications [141]