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By binding G-actin monomers, TB-500 maintains a reservoir of actin that can be rapidly mobilized for filament assembly
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378 On the basis of the increased activity of -gal in senescent cells, a new prodrug, SSK1, which can be specifically cleaved by lysosomal -gal into cytotoxic substances and induce the apoptosis of senescent cells, thereby eliminating senescent cells, was developed
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