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6 Future prospects: innovating potential approaches for gutbone axis to protect bone health 6.1 Disciplinary intersection with nano/molecular medicine Based on the excellent biocompatibility, degradability, and mechanical properties of biomaterials, a variety of nanomaterials have been applied in fracture reposition, bone defect restoration, joint replacement, and bone tumor treatment

Altogether, the metabolic change of C10:2 in PASMCs can drive structural and functional changes of pulmonary vascular by HSP47/NLRP3 axis thus manipulating the PH process

VITAMIN C AND GLUTATHIONE The redox interplay between Vitamin C and glutathione The interaction between vitamin Cand glutathione has been well established, suggesting that they play a central role in cellular antioxidant defense systems