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Compared to patients with primary folate deficiency, those with dihydrofolate reductase deficiency typically exhibit less pronounced developmental abnormalities
It is normally conjugated by glutathione (GSH), but when taken in excess, the body's glutathione reserves are not sufficient to deactivate the toxic NAPQI
Glutathione also aids in our gastrointestinal tract, helping to neutralize harmful compounds before they enter the bloodstream
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