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6 Microvascular endothelial cells that line the vasculature of the BBB are different from other endothelial cells as they lack fenestrations, have more extensive tight junctions, and have reduced pinocytic vesicular transport

Furthermore, another study found the differences in EGCG levels are primarily due to its limited bioavailability

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The ratios of NADH/NAD and NADPH/NADP are significantly altered in rod Igf-1r / mice, suggesting an altered cellular redox and antioxidative imbalance in these mice