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While intramuscular bioavailability is reported at 14-19% in rodent models and 45-51% in canine models, oral bioavailability demonstrates lower but measurable systemic exposure

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For the principal component analysis (PCA) the variance was filtered by default optimisation settings and a predefined standard deviation of p = 0.005 comparing untreated HepG2 and HepG2 ATP7B-KO cells resulted in a false discovery rate (FDR) of q = 0.01788

To make sure the treatment is safe and effective, it is crucial to avoid taking specific medications and supplements before starting it