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Retrieved 14 May 2022, from A Proof of Concept, Phase IIa, Open Label Study to Evaluate the Safety and Efficacy of Subcutaneous Implants of Afamelanotide in Patients with Xeroderma Pigmentosum (XP)

47,48 Glucosidases I and II in the ER progressively remove glucose residues from the N -glycans of newly synthesized glycoproteins to generate Glc 1 Man 9 GlcNAc 2 , which is detected by the calnexin/calreticulin cycle and serves as a signal to promote glycoprotein folding

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