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Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribonucleotides and DNA

doi: 10.1016/j.aca.2011.09.042 29 FuhrerTZamboniN

Measurements were performed using a Triple TOF 5600+ (Sciex, MA, USA) equipped with a DuoSpray IonSource coupled with a Shimadzu Prominence LC20 UFLC (Shimadzu, Japan) system

This method allowed the goodness of fit to inform upon an appropriate model structure when the actual reaction rates were unknown and, in doing so, provided a useful indication of the possible mechanism by which this process occurs