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[DOI] [PMC free article] [PubMed] [Google Scholar] 119.Barisani D, Pelucchi S, Mariani R, Galimberti S, Trombini P, Fumagalli D, Meneveri R, Nemeth E, Ganz T, Piperno A

Conclusions: This study found that avoiding hyperphagia decreases the burden of PWS and that these results are robust, even once imposing strict inclusion criteria

However, when combined with GLP-1 activation, glucagon effects shift dramatically toward beneficial metabolic outcomes