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Why is Glutathione called the Master Antioxidant

In addition, in rat brain, the activities of succinate dehydrogenase (Kugler et al., 1988) and NAD + -dependent IDH3 (Patel, 1977), a rate-limiting step of the citric acid cycle (Chen and Ding, 2023), were also shown to decline with aging (Haripriya et al., 2004), which, together with the loss of ACO2 activity, may be major driving forces behind this oxidizing shift in the neuronal mitochondrial [NAD + ]/[NADH] with aging

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In C 3 plants, NADP-ME is mostly focused with donation of CO 2 residues in biosynthetic pathways as well as maintaining of redox with reduced nicotinamide adenine dinucleotide phosphate [NADP(H)] + H + as equivalent