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People with uncontrolled heart, kidney, or thyroid conditions, those who are pregnant or breastfeeding, and anyone with a history of severe allergic reactions to injectable medications

Regular blood tests are important to monitor thyroid levels and adjust the dosage if necessary

Mechanistically, ART suppressed nuclear localization of SREBP2 in MM cells, accompanied by downregulation of IPP and GPX4, suggesting its capacity to trigger ferroptosis through SREBP2 nuclear localization inhibition and subsequent IPP/GPX4 suppression (Liang et al., 2023)

Natural compounds as adjuvant enhancers in treatment of psoriasis Given the limitations associated with both vitamin D analogs and topical corticosteroidsincluding the risk of cutaneous atrophy, irritation , tachyphylaxis , and limited efficacy in moderate-to-severe psoriasisthere is increasing interest in the use of natural compounds as adjunctive therapies (Bruner et al