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Research indicates that in the early stages of AP, the function of pancreatic -cells may be suppressed by acute stress responses, resulting in reduced insulin secretion

A prominent mechanism in functional GI disorders such as IBS is the modulation of the gut-brain axis

ICMR-INDIAB Study (PIB): Prevalence of Diabetes and Prediabetes in India (101 Million Adults) The Lancet Diabetes & Endocrinology: Metabolic non-communicable disease health report of India: the ICMR-INDIAB national cross-sectional study The STEP 1 Trial (NEJM): Once-Weekly Semaglutide in Adults with Overweight or Obesity The primary clinical trial demonstrating weight loss efficacy

84 noted minor declines (0.7% at one year, 2.3% at two years), though unmeasured vitamin D and PTH levels complicate interpretation