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The Math (So You Can Do It Yourself) Here's the formula for any vial size and any amount of water: Concentration = Peptide Amount (mcg) Water Added (mL) Then to find the injection volume: Units to inject = Desired Dose (mcg) Concentration (mcg/mL) 100 Example: 5,000mcg vial + 2mL water = 2,500mcg/mL

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After consideration of public comments, we are finalizing the CY 2026 update as proposed with a modification to one specialty mapping used in data imputation as described previously