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The effects of corticosteroid medication, increased sunscreen use, and decreased sun exposure are also contributing reasons for this insufficiency (170)
Key Research Characteristics: Extended half-life (~2030 hours vs ~1215 minutes for native IGF-1) due to reduced IGFBP binding Potent agonist at IGF-1R, studied for roles in cellular proliferation, differentiation, and survival signalling Investigated in models of muscle hypertrophy, neuroprotection, and metabolic regulation 83 amino acid analogue
& Whitt, M
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