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Diacylglycerol is released by the degradation of phosphatidylcholine by phospholipases

The N-terminal region also contains other important residues and, indeed, the further truncation of GLP-1, to form GLP-1(15-36)amide, resulted in a 367-fold reduction in affinity (rGLP-1R in CHO cells) and no detectable activity at 1 M peptide (Montrose-Rafizadeh et al ., 1997)

Last, but not least, it has been demonstrated that such drugs can raise energy expenditure, or the number of calories the body burns while at rest