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Gallego-Lopez MDC, Ojeda ML, Romero-Herrera I, et al

R747W is a mutant phenotype with loss-of-function of the gene encoding iPLA2, which reduces the hydrolytic activity of 15-HpETE-PE, and increases the content of 15-HpETE-PE in cells, and increases the sensitivity to ferroptosis compared with the wild type

This can be because women typically have less body water than men who are of comparable body weight, making the alcohol more diluted in mens blood compared to womens

Syringe Units = Volume to Draw (mL) 100 = 0.25 mL 100 = 25 units TB-500 Dosing Profile (10 mg Vial / 1 mL BAC Water) 2.5 mg Dose: Draw 25 units (0.25 mL)