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In certain cases, when symptoms are unusual or to follow-up on abnormal results from the history, exam, and labs, more complex diagnostic tests may be called for, including additional lab work, brain imaging, and others

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Similarly, in atypical odontalgia and certain forms of trigeminal neuralgia, aberrant processing of proprioceptive input has been hypothesized to contribute to altered pain perception, potentially underpinned by abnormal electrophysiological properties of MTNs (Sessle, 2006)