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At the time of discharge (3 months after admission), the patient was able to walk independently, and her weight and BMI had decreased to 104 kg and 50.8 kg/m 2 , respectively (Table 1)

doi: 10.1371/journal.pone.0172604 122 GrabenhorstFRollsETParrisBAdSouzaAA

Key Takeaway: Brief temperature excursions up to 77F are usually tolerated

The second pathway involves the catabolism of L -carnitine through two sequential microbial reactions, first into the intermediate BB, and then into TMA, which is then converted into TMAO by host hepatic FMO3 (Figure 7)